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PROTHROMBIN TIME STUDIES
Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.
Prothrombin is a protein produced by your liver. It is one of the many factors in your blood that help it to clot appropriately. Prothrombin Time (PT) test is used to evaluate blood clotting. It is also used to monitor the drug dose if you are taking the blood thinning medication like Warfarin. Sometimes your doctor may order this test prior to surgery.
It helps with the diagnosis and monitoring of bleeding disorders by determining how long it takes for blood to clot. This test is essential for assessing the blood's ability to clot and produce platelets, which is crucial for treating conditions like hemophilia and estimating the chance of bleeding after surgery or trauma.
Easy bruising
Unexplained heavy bleeding
Unusual blood clots
Blood in urine or stool
Bleeding gums
Unexplained swelling or joint pain
Additionally:
Monitoring patients on specific blood thinners to assess appropriate dosage or need for adjustments
Elevated PT or INR, which suggests insufficient hepatic production of prothrombin, are indicators of prolonged clotting time.
It can be a sign of coagulation problems.
Monitoring these levels helps to adjust the medicine for clotting diseases.
Patients who have bleeding disorders are more prone to encounter excessive bleeding, but there are no specific risks.
It is possible for the injection site to bruise or cause mild pain.
Get in touch with medical experts right away if you encounter any unusual pain or symptoms.
Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.
Daily
H131
N/A
4 hrs
4 hrs
2 weeks
Photo-optical Clot Detection
3 mL Whole blood in 1 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 min. & finally transfer the supernatant (PPP) to 1 labelled clean plastic screw capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory. It is recommended that patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician.
Prothrombin time measures the time it takes for plasma to clot when exposed to tissue factor. Since PT comprises reactions of coagulation that occurs in tissue injury & common pathways of coagulation, deficiencies in the activity of Factors II, V, VII, X or fibrinogen may prolong the PT. INR standardizes the reporting of PT values in Warfarin anticoagulated patients.
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